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1

Process Development of Halaven®: Synthesis of the C14-C35 Fragment via Iterative Nozaki-Hiyama-Kishi Reaction-Williamson Ether Cyclization

Austad, Brian, Benayoud, Farid, Calkins, Trevor, Campagna, Silvio, Chase, Charles, Choi, Hyeong-wook, Christ, William, Costanzo, Robert, Cutter, James, Endo, Atsushi, Fang, Francis, Hu, Yongbo, Lewis,

Journal:

Year:

2013

Language:

english

File:

PDF, 273 KB

english, 2013

2

Encyclopedia of Reagents for Organic Synthesis || Disulfur Dichloride

Austad, Brian C.

Year:

2001

Language:

english

File:

PDF, 322 KB

english, 2001

3

Commercial Manufacture of Halaven®: Chemoselective Transformations En Route to Structurally Complex Macrocyclic Ketones

Austad, Brian, Calkins, Trevor, Chase, Charles, Fang, Francis, Horstmann, Thomas, Hu, Yongbo, Lewis, Bryan, Niu, Xiang, Noland, Thomas, Orr, John, Schnaderbeck, Matthew, Zhang, Huiming, Asakawa, Naoki

Journal:

Year:

2013

Language:

english

File:

PDF, 212 KB

english, 2013

4

A Design of Experiments Approach to a Robust Final Deprotection and Reactive Crystallization of IPI-926, A Novel Hedgehog Pathway Inhibitor

Martinot, Theodore A., Austad, Brian C., Côté, Alexandre, Depew, Kristopher M., Genov, Daniel, Grenier, Louis, Helble, Joseph, Lescarbeau, Andre, Nair, Somarajan, Trudeau, Martin, White, Priscilla, Yu

Journal:

Organic Process Research & Development

Year:

2015

Language:

english

File:

PDF, 5.35 MB

english, 2015

5

Development of a Multi Kilogram-Scale, Tandem Cyclopropanation Ring-Expansion Reaction En Route to Hedgehog Antagonist IPI-926

Austad, Brian C., Hague, Andrew, White, Priscilla, Peluso, Stephane, Nair, Somarajan, Depew, Kristopher, Grogan, Michael, Charette, André B., Yu, Lin-Chen, Lory, Caroline D., Grenier, Louis, Lescarbea

Journal:

Organic Process Research & Development

Year:

2016

Language:

english

File:

PDF, 1.23 MB

english, 2016

6

ChemInform Abstract: Halichondrin B: Synthesis of the C(37)—C(54) Subunit (I).

Brian C. Austad, Amy C. Hart, Steven D. Burke

Journal:

Year:

2002

File:

PDF, 25 KB

2002

7

Pharmaceutical development of IPI-504, an Hsp90 inhibitor and clinical candidate for the treatment of cancer

James R. Porter, Julian Adams, Rebecca Ahn, Vince Ammoscato, Brendan Arsenault, Brian C. Austad, Gary Baker, Johan Basuki, Marlene R. Booth, Matthew J. Campbell, Bennett Carter, Michael Curtis, Kris D

Journal:

Drug Development Research

Year:

2010

Language:

english

File:

PDF, 162 KB

english, 2010

8

Halichondrin B: synthesis of the C(37)–C(54) subunit

Brian C Austad, Amy C Hart, Steven D Burke

Journal:

Year:

2002

Language:

english

File:

PDF, 310 KB

english, 2002

9

Science fact and the SENS agenda

Warner, Huber, Anderson, Julie, Austad, Steven, Bergamini, Ettore, Bredesen, Dale, Butler, Robert, Carnes, Bruce A., Clark, Brian F. C., Cristofalo, Vincent, Faulkner, John

Journal:

Year:

2005

Language:

english

File:

PDF, 39 KB

english, 2005

10

Encyclopedia of Reagents for Organic Synthesis || Sulfur Dichloride

Austad, Brian C.

Year:

2001

Language:

english

File:

PDF, 54 KB

english, 2001

11

Discovery of a Potent and Orally Active Hedgehog Pathway Antagonist (IPI-926)

Tremblay, Martin R., Lescarbeau, André, Grogan, Michael J., Tan, Eddy, Lin, Grace, Austad, Brian C., Yu, Lin-Chen, Behnke, Mark L., Nair, Somarajan J., Hagel, Margit, White, Kerry, Conley, James, Man

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 2.72 MB

english, 2009

12

An Expeditious Synthesis of the C(38)−C(54) Halichondrin B Subunit

Burke, Steven D., Austad, Brian C., Hart, Amy C.

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 54 KB

english, 1998

13

When Should Animals Tolerate Inbreeding?

Peter M. Waser, Steven N. Austad and Brian Keane

Journal:

American Naturalist

Year:

1986

Language:

english

File:

PDF, 784 KB

english, 1986

14

Commercial Manufacture of Halaven®: Chemoselective Transformations En Route to Structurally Complex Macrocyclic Ketones

Austad, Brian, Calkins, Trevor, Chase, Charles, Fang, Francis, Horstmann, Thomas, Hu, Yongbo, Lewis, Bryan, Niu, Xiang, Noland, Thomas, Orr, John, Schnaderbeck, Matthew, Zhang, Huiming, Asakawa, Naoki

Journal:

Year:

2013

File:

PDF, 95 KB

2013

15

When Should Animals Tolerate Inbreeding?

Waser, Peter M., Austad, Steven N., Keane, Brian

Journal:

American Naturalist

Year:

1986

Language:

english

File:

PDF, 721 KB

english, 1986

16

Relationships between drinking quantity and frequency and behavioral and hippocampal BOLD responses during working memory performance involving allocentric spatial navigation in college students

Banz, Barbara C., Worhunsky, Patrick D., Pittman, Brian P., Astur, Robert S., Tennen, Howard A., Raskin, Sarah A., Austad, Carol S., Wood, Rebecca M., Fallahi, Carolyn R., Potenza, Marc N., Pearlson,

Journal:

Drug and Alcohol Dependence

Year:

2019

Language:

english

File:

PDF, 1.03 MB

english, 2019

17

Relationships between drinking quantity and frequency and behavioral and hippocampal BOLD responses during working memory performance involving allocentric spatial navigation in college students

Banz, Barbara C., Worhunsky, Patrick D., Pittman, Brian P., Astur, Robert S., Tennen, Howard A., Raskin, Sarah A., Austad, Carol S., Wood, Rebecca M., Fallahi, Carolyn R., Potenza, Marc N., Pearlson,

Journal:

Drug and Alcohol Dependence

Year:

2019

File:

PDF, 1.03 MB

2019